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Eli Lilly Expects Up to $87 Billion in 2026 Revenue. Here's Why the Stock Still Looks Undervalued.

2026-10-13 09:10 •Adria Cimino •The Motley Fool Positive Axe Cap view: Selective •Equities•Earnings•Healthcare •LLY•NVO

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Eli Lilly’s Growth Surge: Too Big to Ignore but Hard to Play Locally

Eli Lilly’s booming weight loss drug pipeline is lifting revenues sharply, yet South African investors face limited direct access and currency risks.

Eli Lilly’s explosive growth, driven by GLP-1 weight loss drugs like Mounjaro and Zepbound, projects revenues hitting $87 billion in 2026, up from $65 billion this year. That’s big, even if it’s a US pharma story. The company’s valuation, at 32 times forward earnings, seems reasonable considering the pipeline’s promise, such as retatrutide and EloraTZP. However, this isn’t a company you find on the JSE. South African investors relying on offshore exposure should note that a weakening rand against the dollar—USD/ZAR remains volatile around 18.50—could eat into returns. Local financials like Sanlam or FirstRand won't directly benefit from Lilly’s surge but may feel some pressure if rand weakness persists or global growth slows. For anyone without US exposure, this is a reminder to watch the USD/ZAR closely when chasing growth stocks abroad. The view could be wrong if global inflation eases quickly and policy pivots, reducing demand for obesity treatments. this is just our opinion and not financial advice

How I would invest

For South Africans, stick to broad USD exposure or USD/ZAR plays if you want Lilly-like growth. Avoid chasing individual foreign pharma stocks directly without hedging the currency risk. Within local stocks, remain selective in financials until rand volatility settles.

What I would watch
  • USD/ZAR
  • Sanlam
What could go wrong
  • Rand weakness reduces foreign gains
  • US monetary policy tightening impacts pharma valuations
How strongly I feel

6/10

Eli Lilly's weight loss drug portfolio, led by Mounjaro and Zepbound, is driving explosive revenue growth with expectations of up to $87 billion in 2026 revenue compared to $65 billion in 2025. Despite a 400% gain over five years and 25% rise in the past six months, the stock trades at 32x forward earnings—below historical levels—and appears undervalued given strong pipeline candidates like EloraTZP and retatrutide that could further expand the company's weight loss drug offerings.

Our take is based on reporting first published by The Motley Fool.

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